Leon Tai, Ph.D.

Assistant Professor, Anatomy and Cell Biology


Research Interests: Throughout the human body there are specialized, dynamic and complex cellular barriers: the blood-nerve barrier, blood-spinal cord barrier and blood-brain barrier. These barrier interfaces play a central role in homeostasis and neuronal function, through preventing the uptake of unwanted molecules, removing waste products, supplying essential nutrients and signaling molecules, and modulating inflammation. Our goal is to identify and therapeutically target mechanistic pathways that underlie barrier and neuronal dysfunction in aging and neurodegenerative disorders including Alzheimer's disease, chronic pain, ALS and metabolic dysfunction.

Office: Room 567B CME
Phone: 312-996-2296
E-mail address: Email:


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